The relevance of this article is determined by the need to study the difficulties facing young people in the process of social adaptation during quarantine on the back of the coronavirus pandemic. Due to their worldview that is often in conflict with the surrounding social environment, as well as their life attitudes and inability to adapt to the situation, young people may not be able to cope with all the processes of social adaptation that occur every now and then in everyday life. In the context of the quarantine announced to curb the spread of coronavirus, some young people may experience increased social maladaptation and develop psychosocial fears. This article is aimed at identifying the specifics of the relationship between adaptation strategies and disorders caused by social stresses in college students in the situation of temporary involuntary isolation (under quarantine). We used a questionnaire survey as a research methodology to identify both social adaptation strategies of math students and disorders associated with social stresses that they may develop in the situation of temporary involuntary isolation. The article has revealed strategies for the social adaptation of math students in the situation of quarantine. The article analyses the relationship between the social adaptation strategy and social stress disorders of math students during the coronavirus pandemic. The data obtained in this research can be used in social psychology, pedagogy, age psychology, medical psychology, as well as for further theoretical development of this problem.