Business Statistics is an important course for teaching administration and business colleges in colleges and universities. In most colleges and universities, traditional “teaching” mode is till used in course teaching of business Statistics; the mode of interfered realization of course teaching goal in a certain extent. In this essay, current status and characteristics of course teaching of Business Statistics were sorted out with guidance of information age background. The study suggested that there were following problems in course teaching of Business Statistics: defects of teaching position, “teaching-learning” was main mode, connection with practical demands was not close enough and etc. In the study, overall reform framework was proposed through content, method and evaluation of course teaching; “Practical Business Statistics” was conducted and used; teaching reform mode with theories and practical teaching was formed which could provide reference for course teaching reform of Business Statistics in colleges and universities.